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VENOUS INSUFFICIENCY

PELVIC CONGESTION SYNDROME

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Approximately 15% of women aged 20-50 have pelvic vein insufficiency, with 60% of them being symptomatic. This condition typically affects the left side and is effectively treatable.

Symptoms

  • Bloating
  • Nausea
  • Vaginal discharge
  • Swelling in the pubic area
  • Lower back pain
  • Pain in the anal region
  • Urge incontinence
  • Hip pain
  • Leg varicose veins
  • Sexual arousal
  • Dyspareunia
  • Possible irritable bowel syndrome (IBS)

Presentation

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Anatomy

Risk factors
* Pregnancy
* Previous pelvic surgery
* Estrogen therapy
* Obesity, phlebitis
* Heavy lifting
* Venous anomalies
* Endometriosis, fibroids
* Tumors
* Genetic predispositions such as FOXC2, TIE2, NOTCH3
* Thrombomodulin
* Type 2 transforming growth factor-β receptor
* There is an association with polycystic ovaries
* During pregnancy, venous capacity increases by 60%, potentially leading to valve incompetence

Indications

Type

Description

Treatment

I

Venous insufficiency[colspan="2"]

[null]

Ia

Unilateral venous insufficiency

Embolization

Ib

Bilateral venous insufficiency

Embolization

II

Venous compression[colspan="2"]

[null]

IIa

May-Thurner syndrome

Stenting ± embolization

IIb

Nutcracker phenomenon

Embolization ± stenting

IIc

May-Thurner syndrome and nutcracker phenomenon

Stenting, embolization

IId

Other extrinsic venous compression

Stenting

III

Venous obstruction[colspan="2"]

[null]

IIIa

Common iliac vein obstruction

Stenting

IIIb

Inferior vena cava obstruction

Stenting

IIIc

Portal hypertension

Stenting

IV

Arteriovenous malformation or fistula

Embolization

V

Nutcracker syndrome

Stenting or surgery

Contra Indications

Workup

SVP

S - symptoms [colspan="2"]

[null]

S0

No symptoms

S1

Renal symptoms of venous origin

S2

Chronic pelvic pain of venous origin

S3

Extra-pelvic symptoms of venous origin

  • Localized symptoms associated with pelvic origin
  • non-saphenous veins of the leg
  • Venous claudication

V - varices [colspan="2"]

[null]

V0

No abdominal, pelvic, or pelvic origin extra-pelvic varices

V1

Renal hilar varices

V2

Pelvic varices

V3

Pelvic origin extra-pelvic varices

  • Genital varices (vulvar varices and varicocele)
  • Pelvic origin lower extremity varicose veins arising from the pelvic escape points and extending into the thigh

P - pathophysiology [colspan="2"]

[null]

Anatomy[colspan="2"]

[null]

IVC

Inferior vena cava

LRV

Left renal vein

LGV
RGV
BGV

Left gonadal vein
Right gonadal vein
Bilateral gonadal veins

LCIV
RCIV
BCIV

Left common iliac vein
Right common iliac vein
Bilateral common iliac veins

LEIV
REIV
BEIV

Left external iliac vein
Right external iliac vein
Bilateral external iliac veins

IIV
LIIV
RIIV
BIIV

Internal iliac vein
Left internal iliac vein
Right internal iliac vein
Bilateral internal iliac veins

PELV

Pelvic escape veins

  • Inguinal
  • Obturator
  • Pudendal and/or gluteal

Hemodynamics[colspan="2"]

[null]

O

Obstruction—thrombotic or nonthrombotic

R

Reflux—thrombotic or nonthrombotic

Ethiology[colspan="2"]

[null]

T

Thrombotic—venous reflux or obstruction after a DVT

N

Nonthrombotic—reflux arising from a degenerative process of the vein wall or proximal obstruction; obstruction arising from extrinsic compression

C

Congenital—congenital venous or mixed vascular malformation

Multiple imaging modalities—ultrasound, venography (with or without intravascular ultrasound), computed tomography (CT), and magnetic resonance imaging (MRI)—are used to evaluate pelvic venous disorders. Because definitive anatomic and hemodynamic criteria for the PeVD spectrum remain lacking, no noninvasive imaging study alone should be used as the sole justification for intervention. Imaging findings must be interpreted cautiously and correlated carefully with the patient’s clinical symptoms.

Preproduceral

DRUGS TO STOP
  • Transabdominal and transvaginal ultrasound
  • Computed tomography venography (CTV)
  • Magnetic resonance venography

Material

Essentials

  • Ultrasound
  • Chlorhexidine
  • Standard angiography set
  • Sterile drapes
  • Lidocaine 1% 10 ml
  • Contrast medium
  • Heparine 5.000 IU/ml
  • Heparinized saline (5.000 IU/l)
  • 6F Introducer
  • RIM catheter
  • 25-45 cm 6F sheaths
  • Stiff Terumo wire
  • Floppy Terumo wire
  • Cobra catheters
  • Glubran2
  • Coils, both pushable/detachable and 0.018" and 0.035"

Non Essentials

Write your text here

Positioning

  • Head first
  • Supine

Steps

  • Time out
  • Infiltration with Lidocaine
  • Ultrasound-guided venous puncture
  • Placement of a sheath
  • Administration of Heparin (5000 IU)
  • Selective catheterization of the left renal vein
  • Deep renal vein series under Valsalva maneuver
  • If possible direct catheterization of the left ovarian vein, and if insufficient embolization with Glubran2
  • Identification of the right ovarian vein, same procedrue as left ovarian vein
  • Selective catheterization of the iliac veins, if insufficient embolization with coils
  • Closure by manual compression

Tips & Tricks

  • In case of perforation, avoid gluing due to the risk of damaging the ureter

Complications

COMPLICATIONS
Access site complications, hematoma, pseudoaneurysm, fistula 0.4%
Testicular pain post-procedure, may last up to 10 days
Spasm, perforation
Coil migration, rare when the correct coil size is used
Pelvic vein thrombosis
Phlebitis, occurs only with sclerotherapy (typically begins 24-48 hours post-procedure)
Post-embolization syndrome
Recurrence 2-24%

Postoperative

DRUGS TO START
  • Bed rest for around 2 h

Follow up

  • In case of recurrent or persistent symptoms

Folder

Literature

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Report

Time out.
Wassen met chloorhexidine en steriel afdekken. Echografisch geen stenose in de VFCD. Antegrade toegang, met 6F sheath. 5000 IE Heparine.

Selectieve katheterisatie van de vene renalis links. Er wordt geen insufficient collateraal pad gezien vanuit diepe renale vene. De vene ovarica is sufficient.

De vene ovarica rechts wordt niet geidentificeerd en als sufficient beschouwd. Geen insufficiente konvoluten in de ilacale venen.

Manuele compressie.
Sign-out

Time-out.
Cleanse with chlorhexidine and drape sterilely. Ultrasound shows no stenosis in the common femoral vein. Obtained antegrade access and placed a 6F sheath. Administered 5,000 IU heparin.

Selective catheterization of the left renal vein was performed. No insufficient collateral pathway from the deep renal vein was identified. The left ovarian vein is competent.

The right ovarian vein was not visualized; it is presumed competent. No insufficient varicosities were seen in the iliac veins.

Manual compression applied.
Sign-out

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