Pulmonary embolism (PE) continues to be a major cause of morbidity and mortality. Estimates of the incidence of non-fatal PE range from 400,000-630,000 cases per year and 50,000-200,000 fatalities per year directly attributable to PE. The current preferred treatment for deep venous thrombosis (DVT) and PE is anticoagulation. However, up to 20% of these patients will have recurrent PE.
Interruption of the inferior vena cava (IVC) for the prevention of PE was first performed in 1893 using surgical ligation. Over the years, surgical interruption took many forms (ligation, plication, clipping, or stapling) but IVC thrombosis was a frequent complication after these procedures. Endovascular approaches to IVC interruption became a reality in 1967 after the introduction of the Mobin-Uddin filter.
In recent years, filter technology has therefore focused on means to afford temporary protection for those patients with short-term risk of PE (e.g. patients undergoing orthopaedic surgery, patients with temporary contraindication to anticoagulation, patients undergoing thrombolysis for deep venous thrombosis [DVT], and patients whose anticoagulation requires temporary cessation due to surgery). These patients are often young or have an otherwise normal life expectancy.
This has led to the development of temporary tethered filters that must be removed within 2 weeks of insertion and retrievable IVC filters (without tether) that can be retrieved or left in place as permanent filters. The permanent option of the retrievable filter is especially suitable for those patients where uncertainty exists regarding the ethiology of the thrombosis and may in retrospect require permanent partial vena cava interruption.
1. Iliac segment from the posterior cardinal veins
2. Subrenal segment from the right supracardinal vein
3. Renal segment from the anastomosis between the right supracardinal and subcardinal veins
4. Suprarenal segment from the right subcardinal vein
5. Hepatic segment from the hepatocardiac canal.
Patients with evidence of pulmonary embolus or IVC, iliac, or femoral-popliteal DVT and one or more of the following:
Published rates for individual types of complications are highly dependent on patient selection and are, in some cases, based on series comprising several hundred patients, which is a volume larger than most individual practitioners are likely to treat. It is also recognised that a single complication can cause a rate to cross above a complication-specific threshold when the complication occurs in a small volume of patients, e.g. early in a quality improvement programme.
Clinically significant penetration and migration are felt to be rare. The rate of clinically significant penetration is undefined in the literature.
| Complication | Reported rate (%) | Threshold (%) |
| Death | 0,12 | <1 |
| Recurrent PE | 0,5-6 | 5 |
| IVC Occlusion | 2-30 | 10 |
| Filter embolisation | 2-5 | 2 |
| Access site thrombosis | 0-6 | 1 |
| Migration | 0-18 | |
| Fracture | 2-10 | |
| Perforation | 0-41 |
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